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Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation
SARS-CoV-2 is a betacoronavirus virus responsible for the COVID-19 pandemic. Here, we determine the X-ray crystal structure of a potent neutralizing monoclonal antibody, CV30, isolated from a patient infected with SARS-CoV-2, in complex with the receptor binding domain. The structure reveals that CV...
में बचाया:
| में प्रकाशित: | Nat Commun |
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| मुख्य लेखकों: | , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group UK
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7591918/ https://ncbi.nlm.nih.gov/pubmed/33110068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19231-9 |
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