Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual

B cells specific for the SARS-CoV-2 S envelope glycoprotein spike were isolated from a COVID-19-infected subject using a stabilized spike-derived ectodomain (S2P) twenty-one days post-infection. Forty-four S2P-specific monoclonal antibodies were generated, three of which bound to the receptor bindin...

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Udgivet i:bioRxiv
Main Authors: Seydoux, Emilie, Homad, Leah J., MacCamy, Anna J., Parks, K. Rachael, Hurlburt, Nicholas K., Jennewein, Madeleine F., Akins, Nicholas R., Stuart, Andrew B., Wan, Yu-Hsin, Feng, Junli, Nelson, Rachael E., Singh, Suruchi, Cohen, Kristen W., McElrath, M. Juliana, Englund, Janet A., Chu, Helen Y., Pancera, Marie, McGuire, Andrew T., Stamatatos, Leonidas
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241105/
https://ncbi.nlm.nih.gov/pubmed/32511342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.05.12.091298
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