Early stage prion assembly involves two subpopulations with different quaternary structures and a secondary templating pathway

The dynamics of aggregation and structural diversification of misfolded, host-encoded proteins in neurodegenerative diseases are poorly understood. In many of these disorders, including Alzheimer’s, Parkinson’s and prion diseases, the misfolded proteins are self-organized into conformationally disti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Igel-Egalon, Angélique, Laferrière, Florent, Moudjou, Mohammed, Bohl, Jan, Mezache, Mathieu, Knäpple, Tina, Herzog, Laetitia, Reine, Fabienne, Jas-Duval, Christelle, Doumic, Marie, Rezaei, Human, Béringue, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778151/
https://ncbi.nlm.nih.gov/pubmed/31602412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0608-y
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados