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Early stage prion assembly involves two subpopulations with different quaternary structures and a secondary templating pathway
The dynamics of aggregation and structural diversification of misfolded, host-encoded proteins in neurodegenerative diseases are poorly understood. In many of these disorders, including Alzheimer’s, Parkinson’s and prion diseases, the misfolded proteins are self-organized into conformationally disti...
Guardat en:
| Publicat a: | Commun Biol |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6778151/ https://ncbi.nlm.nih.gov/pubmed/31602412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0608-y |
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