Regulation of histone methylation by automethylation of PRC2

Polycomb-repressive complex 2 (PRC2) is a histone methyltransferase that is critical for regulating transcriptional repression in mammals. Its catalytic subunit, EZH2, is responsible for the trimethylation of H3K27 and also undergoes automethylation. Using mass spectrometry analysis of recombinant h...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Wang, Xueyin, Long, Yicheng, Paucek, Richard D., Gooding, Anne R., Lee, Thomas, Burdorf, Rachel M., Cech, Thomas R.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2019
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771386/
https://ncbi.nlm.nih.gov/pubmed/31488576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.328849.119
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