Regulation of histone methylation by automethylation of PRC2

Polycomb-repressive complex 2 (PRC2) is a histone methyltransferase that is critical for regulating transcriptional repression in mammals. Its catalytic subunit, EZH2, is responsible for the trimethylation of H3K27 and also undergoes automethylation. Using mass spectrometry analysis of recombinant h...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Wang, Xueyin, Long, Yicheng, Paucek, Richard D., Gooding, Anne R., Lee, Thomas, Burdorf, Rachel M., Cech, Thomas R.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771386/
https://ncbi.nlm.nih.gov/pubmed/31488576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.328849.119
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