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Towards a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA

Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Early works suggested binding specificity of PRC2 to certain long non-coding RNAs for recruitment to chromatin. More recent studies provided evidence both in favor and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Davidovich, Chen, Wang, Xueyin, Cifuentes-Rojas, Catherine, Goodrich, Karen J., Gooding, Anne R., Lee, Jeannie T., Cech, Thomas R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320675/
https://ncbi.nlm.nih.gov/pubmed/25601759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.017
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