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Towards a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA
Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Early works suggested binding specificity of PRC2 to certain long non-coding RNAs for recruitment to chromatin. More recent studies provided evidence both in favor and...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320675/ https://ncbi.nlm.nih.gov/pubmed/25601759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.017 |
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