Regulation of histone methylation by automethylation of PRC2

Polycomb-repressive complex 2 (PRC2) is a histone methyltransferase that is critical for regulating transcriptional repression in mammals. Its catalytic subunit, EZH2, is responsible for the trimethylation of H3K27 and also undergoes automethylation. Using mass spectrometry analysis of recombinant h...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Wang, Xueyin, Long, Yicheng, Paucek, Richard D., Gooding, Anne R., Lee, Thomas, Burdorf, Rachel M., Cech, Thomas R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2019
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771386/
https://ncbi.nlm.nih.gov/pubmed/31488576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.328849.119
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