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Regulation of histone methylation by automethylation of PRC2

Polycomb-repressive complex 2 (PRC2) is a histone methyltransferase that is critical for regulating transcriptional repression in mammals. Its catalytic subunit, EZH2, is responsible for the trimethylation of H3K27 and also undergoes automethylation. Using mass spectrometry analysis of recombinant h...

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Dades bibliogràfiques
Publicat a:Genes Dev
Autors principals: Wang, Xueyin, Long, Yicheng, Paucek, Richard D., Gooding, Anne R., Lee, Thomas, Burdorf, Rachel M., Cech, Thomas R.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771386/
https://ncbi.nlm.nih.gov/pubmed/31488576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.328849.119
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