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Competition between PRC2.1 and 2.2 Subcomplexes Regulates PRC2 Chromatin Occupancy in Human Stem Cells
Polycomb repressive complex 2 (PRC2) silences the expression of developmental transcription factors in pluripotent stem cells by methylating lysine 27 on histone H3. Two mutually exclusive subcomplexes, PRC2.1 and PRC2.2, are defined by the set of accessory proteins bound to the core PRC2 subunits....
Tallennettuna:
| Julkaisussa: | Mol Cell |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7867654/ https://ncbi.nlm.nih.gov/pubmed/33338397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.11.044 |
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