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The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2

Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Among chromatin modifying factors shown to be recruited and regulated by long noncoding RNAs (lncRNAs), PRC2 is one of the most studied. Mammalian PRC2 binds thousands...

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Detalles Bibliográficos
Publicado en:RNA
Autores principales: Davidovich, Chen, Cech, Thomas R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647455/
https://ncbi.nlm.nih.gov/pubmed/26574518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.053918.115
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