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The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2

Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Among chromatin modifying factors shown to be recruited and regulated by long noncoding RNAs (lncRNAs), PRC2 is one of the most studied. Mammalian PRC2 binds thousands...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Davidovich, Chen, Cech, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647455/
https://ncbi.nlm.nih.gov/pubmed/26574518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.053918.115
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