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Promiscuous RNA binding by Polycomb Repressive Complex 2
Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Long non-coding RNAs (lncRNAs) recruit PRC2 to chromatin, but the general role of RNA in maintaining repressed chromatin is unknown. Here we measure the binding consta...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823624/ https://ncbi.nlm.nih.gov/pubmed/24077223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2679 |
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