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ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets
X chromosome inactivation (XCI) depends on the long noncoding RNA Xist and its recruitment of Polycomb Repressive Complex 2 (PRC2). PRC2 is also targeted to other sites throughout the genome to effect transcriptional repression. Using XCI as a model, we apply an unbiased proteomics approach to isola...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4379047/ https://ncbi.nlm.nih.gov/pubmed/25417162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.019 |
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