Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function

Heterochromatin in the eukaryotic genome is rigorously controlled by the concerted action of protein factors and RNAs. Here, we investigate the RNA binding function of ATRX, a chromatin remodeler with roles in silencing of repetitive regions of the genome and in recruitment of the polycomb repressiv...

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Publicat a:Nat Commun
Autors principals: Ren, Wenqing, Medeiros, Nicole, Warneford-Thomson, Robert, Wulfridge, Phillip, Yan, Qingqing, Bian, Joyce, Sidoli, Simone, Garcia, Benjamin A., Skordalakes, Emmanuel, Joyce, Eric, Bonasio, Roberto, Sarma, Kavitha
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203109/
https://ncbi.nlm.nih.gov/pubmed/32376827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15902-9
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