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Mutant ATRX: uncovering a new therapeutic target for glioma
INTRODUCTION: ATRX is a chromatin remodeling protein whose main function is the deposition of the histone variant H3.3. ATRX mutations are widely distributed in glioma, and correlate with alternative lengthening of telomeres (ALT) development, but they also affect other cellular functions related to...
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| Publicado no: | Expert Opin Ther Targets |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044414/ https://ncbi.nlm.nih.gov/pubmed/29889582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2018.1487953 |
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