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Mutant ATRX: uncovering a new therapeutic target for glioma

INTRODUCTION: ATRX is a chromatin remodeling protein whose main function is the deposition of the histone variant H3.3. ATRX mutations are widely distributed in glioma, and correlate with alternative lengthening of telomeres (ALT) development, but they also affect other cellular functions related to...

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Bibliografiske detaljer
Udgivet i:Expert Opin Ther Targets
Main Authors: Haase, Santiago, Garcia-Fabiani, María Belén, Carney, Stephen, Altshuler, David, Núñez, Felipe J., Méndez, Flor M., Núñez, Fernando, Lowenstein, Pedro R., Castro, Maria G.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044414/
https://ncbi.nlm.nih.gov/pubmed/29889582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2018.1487953
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