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Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach
R-loops are three-stranded DNA:RNA hybrids that are implicated in many nuclear processes. While R-loops may have physiological roles, the formation of stable, aberrant R-loops has been observed in neurological disorders and cancers. Current methods to assess their genome-wide distribution rely on af...
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| Vydáno v: | Cell Rep |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6870988/ https://ncbi.nlm.nih.gov/pubmed/31665646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.09.052 |
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