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Jpx RNA Activates Xist by Evicting CTCF
In mammals, dosage compensation between XX and XY individuals occurs through X chromosome inactivation (XCI). The noncoding Xist RNA is expressed and initiates XCI only when more than one X chromosome is present. Current models invoke a dependency on the X-to-autosome ratio (X:A), but molecular fact...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777401/ https://ncbi.nlm.nih.gov/pubmed/23791181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.05.028 |
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