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Jpx RNA Activates Xist by Evicting CTCF

In mammals, dosage compensation between XX and XY individuals occurs through X chromosome inactivation (XCI). The noncoding Xist RNA is expressed and initiates XCI only when more than one X chromosome is present. Current models invoke a dependency on the X-to-autosome ratio (X:A), but molecular fact...

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Bibliografiske detaljer
Main Authors: Sun, Sha, Del Rosario, Brian C., Szanto, Attila, Ogawa, Yuya, Jeon, Yesu, Lee, Jeannie T.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777401/
https://ncbi.nlm.nih.gov/pubmed/23791181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.05.028
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