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The long noncoding RNA, Jpx, is a molecular switch for X-chromosome inactivation
Once protein-coding, the X-inactivation center (Xic) is now dominated by large noncoding RNAs (ncRNA). X-chromosome inactivation (XCI) equalizes gene expression between mammalian males and females by inactivating one X in female cells. XCI requires Xist, a ncRNA that coats the X and recruits Polycom...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2994261/ https://ncbi.nlm.nih.gov/pubmed/21029862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.09.049 |
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