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YY1 tethers Xist RNA to the inactive X nucleation center
The long noncoding Xist RNA inactivates one X-chromosome in the female mammal. Current models posit that Xist induces silencing as it spreads along X and recruits Polycomb complexes. However, the mechanisms for Xist loading and spreading are currently unknown. Here, we define the nucleation center f...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150513/ https://ncbi.nlm.nih.gov/pubmed/21729784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.06.026 |
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