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Xist RNA antagonizes the SWI/SNF chromatin remodeler BRG1 on the inactive X chromosome
The noncoding RNA Xist recruits silencing factors to the inactive X chromosome (Xi) and facilitates re-organization of Xi structure. Here, we examine the mouse epigenomic landscape of Xi and assess how Xist alters chromatin accessibility. Interestingly, Xist deletion triggers a gain of accessibility...
Tallennettuna:
| Julkaisussa: | Nat Struct Mol Biol |
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| Päätekijät: | , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6421574/ https://ncbi.nlm.nih.gov/pubmed/30664740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0176-8 |
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