Xist RNA antagonizes the SWI/SNF chromatin remodeler BRG1 on the inactive X chromosome

The noncoding RNA Xist recruits silencing factors to the inactive X chromosome (Xi) and facilitates re-organization of Xi structure. Here, we examine the mouse epigenomic landscape of Xi and assess how Xist alters chromatin accessibility. Interestingly, Xist deletion triggers a gain of accessibility...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Struct Mol Biol
Autors principals: Jégu, Teddy, Blum, Roy, Cochrane, Jesse C., Yang, Lin, Wang, Chen-Yu, Gilles, Maud-Emmanuelle, Colognori, David, Szanto, Attila, Marr, Sharon K., Kingston, Robert E., Lee, Jeannie T.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421574/
https://ncbi.nlm.nih.gov/pubmed/30664740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0176-8
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars