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Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development
Inactivation of Brg1 and Brm accelerated lung tumor development, shortened tumor latency, and caused a loss of differentiation. Tumors with Brg1 and/or Brm loss recapitulated the evolution of human lung cancer as observed by the development of local tumor invasion as well as distal tumor metastasis,...
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| 出版年: | Oncoscience |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5235921/ https://ncbi.nlm.nih.gov/pubmed/28105457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.323 |
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