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Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development
Inactivation of Brg1 and Brm accelerated lung tumor development, shortened tumor latency, and caused a loss of differentiation. Tumors with Brg1 and/or Brm loss recapitulated the evolution of human lung cancer as observed by the development of local tumor invasion as well as distal tumor metastasis,...
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| Publicat a: | Oncoscience |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5235921/ https://ncbi.nlm.nih.gov/pubmed/28105457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.323 |
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