The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors

Rhabdoid sarcomas are highly malignant tumors that usually occur in young children. A key to the genesis of this tumor is the mutational loss of the BAF47 gene as well as the widespread epigenetic suppression of other key anticancer genes. The BRM gene is one such epigenetically silenced gene in Rha...

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Библиографические подробности
Главные авторы: Kahali, Bhaskar, Yu, Jinlong, Marquez, Stefanie B., Thompson, Kenneth. W., Liang, Shermi Y., Lu, Li, Reisman, David
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2014
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102812/
https://ncbi.nlm.nih.gov/pubmed/24913006
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