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Growth inhibition by the mammalian SWI–SNF subunit Brm is regulated by acetylation

In mammalian cells, the SWI–SNF chromatin-remodeling complex is a regulator of cell proliferation, and overexpression of the catalytic subunit Brm interferes with cell cycle progression. Here, we show that treatment with histone deacetylase (HDAC) inhibitors reduces the inhibitory effect of Brm on t...

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Detalhes bibliográficos
Main Authors: Bourachot, Brigitte, Yaniv, Moshe, Muchardt, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC291816/
https://ncbi.nlm.nih.gov/pubmed/14657023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg621
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