Growth inhibition by the mammalian SWI–SNF subunit Brm is regulated by acetylation
In mammalian cells, the SWI–SNF chromatin-remodeling complex is a regulator of cell proliferation, and overexpression of the catalytic subunit Brm interferes with cell cycle progression. Here, we show that treatment with histone deacetylase (HDAC) inhibitors reduces the inhibitory effect of Brm on t...
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| Udgivet i: | EMBO J |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291816/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg621 |
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