Growth inhibition by the mammalian SWI–SNF subunit Brm is regulated by acetylation

In mammalian cells, the SWI–SNF chromatin-remodeling complex is a regulator of cell proliferation, and overexpression of the catalytic subunit Brm interferes with cell cycle progression. Here, we show that treatment with histone deacetylase (HDAC) inhibitors reduces the inhibitory effect of Brm on t...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Bourachot, Brigitte, Yaniv, Moshe, Muchardt, Christian
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291816/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg621
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