Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia

Obesity is associated with metabolic endotoxemia, reactive oxygen species (ROS), chronic inflammation, and obese kidney fibrosis. Although the fat–intestine–kidney axis has been documented, the pathomechanism and therapeutic targets of obese kidney fibrosis remain unelucidated. To mimic obese humans...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chang, Jia-Feng, Yeh, Jih-Chen, Ho, Chun-Ta, Liu, Shih-Hao, Hsieh, Chih-Yu, Wang, Ting-Ming, Chang, Shu-Wei, Lee, I-Ta, Huang, Kuo-Yang, Wang, Jen-Yu, Lin, Wei-Ning
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769974/
https://ncbi.nlm.nih.gov/pubmed/31500176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184393
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