Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia

Obesity is associated with metabolic endotoxemia, reactive oxygen species (ROS), chronic inflammation, and obese kidney fibrosis. Although the fat–intestine–kidney axis has been documented, the pathomechanism and therapeutic targets of obese kidney fibrosis remain unelucidated. To mimic obese humans...

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Publicado en:Int J Mol Sci
Autores principales: Chang, Jia-Feng, Yeh, Jih-Chen, Ho, Chun-Ta, Liu, Shih-Hao, Hsieh, Chih-Yu, Wang, Ting-Ming, Chang, Shu-Wei, Lee, I-Ta, Huang, Kuo-Yang, Wang, Jen-Yu, Lin, Wei-Ning
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769974/
https://ncbi.nlm.nih.gov/pubmed/31500176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184393
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