Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia

Obesity is associated with metabolic endotoxemia, reactive oxygen species (ROS), chronic inflammation, and obese kidney fibrosis. Although the fat–intestine–kidney axis has been documented, the pathomechanism and therapeutic targets of obese kidney fibrosis remain unelucidated. To mimic obese humans...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Chang, Jia-Feng, Yeh, Jih-Chen, Ho, Chun-Ta, Liu, Shih-Hao, Hsieh, Chih-Yu, Wang, Ting-Ming, Chang, Shu-Wei, Lee, I-Ta, Huang, Kuo-Yang, Wang, Jen-Yu, Lin, Wei-Ning
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769974/
https://ncbi.nlm.nih.gov/pubmed/31500176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184393
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