Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia

Obesity is associated with metabolic endotoxemia, reactive oxygen species (ROS), chronic inflammation, and obese kidney fibrosis. Although the fat–intestine–kidney axis has been documented, the pathomechanism and therapeutic targets of obese kidney fibrosis remain unelucidated. To mimic obese humans...

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Udgivet i:Int J Mol Sci
Main Authors: Chang, Jia-Feng, Yeh, Jih-Chen, Ho, Chun-Ta, Liu, Shih-Hao, Hsieh, Chih-Yu, Wang, Ting-Ming, Chang, Shu-Wei, Lee, I-Ta, Huang, Kuo-Yang, Wang, Jen-Yu, Lin, Wei-Ning
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769974/
https://ncbi.nlm.nih.gov/pubmed/31500176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184393
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