Exposure to growth hormone is associated with hepatic up-regulation of cPLA2α and COX

Continuously elevated levels of growth hormone (GH) during life in mice are associated with hepatomegaly due to hepatocytes hypertrophy and hyperplasia, chronic liver inflammation, elevated levels of arachidonic acid (AA) at young ages and liver tumors development at old ages. In this work, the hepa...

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Foilsithe in:Mol Cell Endocrinol
Main Authors: Piazza, Verónica G, Matzkin, María E, Cicconi, Nadia S, Muia, Nadia V, Valquinta, Sofía, Mccallum, Gregorio J, Micucci, Giannina P, Freund, Thomas, Zotta, Elsa, González, Lorena, Frungieri, Mónica B, Fang, Yimin, Bartke, Andrzej, Sotelo, Ana I, Miquet, Johanna G
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211091/
https://ncbi.nlm.nih.gov/pubmed/32259636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2020.110802
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