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Exposure to growth hormone is associated with hepatic up-regulation of cPLA2α and COX

Continuously elevated levels of growth hormone (GH) during life in mice are associated with hepatomegaly due to hepatocytes hypertrophy and hyperplasia, chronic liver inflammation, elevated levels of arachidonic acid (AA) at young ages and liver tumors development at old ages. In this work, the hepa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Endocrinol
Prif Awduron: Piazza, Verónica G, Matzkin, María E, Cicconi, Nadia S, Muia, Nadia V, Valquinta, Sofía, Mccallum, Gregorio J, Micucci, Giannina P, Freund, Thomas, Zotta, Elsa, González, Lorena, Frungieri, Mónica B, Fang, Yimin, Bartke, Andrzej, Sotelo, Ana I, Miquet, Johanna G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211091/
https://ncbi.nlm.nih.gov/pubmed/32259636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2020.110802
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