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β-Lactones: A Novel Class of Ca(2+)-Independent Phospholipase A(2) (Group VIA iPLA(2)) Inhibitors with Ability to Inhibit β-Cell Apoptosis
Interest in Ca(2+)-independent phospholipase A(2) (GVIA iPLA(2)) has accelerated recently as it is being recognized as a participant in biological processes underlying diabetes development and autoimmune-based neurological disorders. The development of potent GVIA iPLA(2) inhibitors is of great impo...
Kaydedildi:
| Yayımlandı: | J Med Chem |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6767909/ https://ncbi.nlm.nih.gov/pubmed/30798607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b01216 |
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