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Group VIA Ca(2+)-Independent Phospholipase A(2)β (iPLA(2)β) and its role in β-cell Programmed Cell Death

Activation of phospholipases A(2) (PLA(2)s) leads to the generation of biologically active lipid mediators that can affect numerous cellular events. The Group VIA Ca(2+)-independent PLA(2), designated iPLA(2)®, is active in the absence of Ca(2+), activated by ATP, and inhibited by the bromoenol lact...

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Bibliographic Details
Main Authors: Lei, Xiaoyong, Barbour, Suzanne E., Ramanadham, Sasanka
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878874/
https://ncbi.nlm.nih.gov/pubmed/20083151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2010.01.005
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