Highly Potent 2-Oxoester Inhibitors of Cytosolic Phospholipase A(2) (GIVA cPLA(2))

[Image: see text] Cytosolic phospholipase A(2) (GIVA cPLA(2)) has attracted great interest as a medicinal target because it initiates the eicosanoid cascade and is involved in a number of inflammatory diseases. As a consequence, the development of potent synthetic inhibitors is of great importance....

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Vydáno v:ACS Omega
Hlavní autoři: Psarra, Anastasia, Kokotou, Maroula G., Galiatsatou, Gerasimia, Mouchlis, Varnavas D., Dennis, Edward A., Kokotos, George
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2018
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120731/
https://ncbi.nlm.nih.gov/pubmed/30197994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01214
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