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Control of Growth Cone Motility and Morphology by LIM Kinase and Slingshot via Phosphorylation and Dephosphorylation of Cofilin

Growth cone motility and morphology are based on actin-filament dynamics. Cofilin plays an essential role for the rapid turnover of actin filaments by severing and depolymerizing them. The activity of cofilin is repressed by phosphorylation at Ser3 by LIM kinase (LIMK, in which LIM is an acronym of...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Endo, Mitsuharu, Ohashi, Kazumasa, Sasaki, Yukio, Goshima, Yoshio, Niwa, Ryusuke, Uemura, Tadashi, Mizuno, Kensaku
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742113/
https://ncbi.nlm.nih.gov/pubmed/12684437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-07-02527.2003
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