Control of Growth Cone Motility and Morphology by LIM Kinase and Slingshot via Phosphorylation and Dephosphorylation of Cofilin

Growth cone motility and morphology are based on actin-filament dynamics. Cofilin plays an essential role for the rapid turnover of actin filaments by severing and depolymerizing them. The activity of cofilin is repressed by phosphorylation at Ser3 by LIM kinase (LIMK, in which LIM is an acronym of...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Endo, Mitsuharu, Ohashi, Kazumasa, Sasaki, Yukio, Goshima, Yoshio, Niwa, Ryusuke, Uemura, Tadashi, Mizuno, Kensaku
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742113/
https://ncbi.nlm.nih.gov/pubmed/12684437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-07-02527.2003
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