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Control of Growth Cone Motility and Morphology by LIM Kinase and Slingshot via Phosphorylation and Dephosphorylation of Cofilin

Growth cone motility and morphology are based on actin-filament dynamics. Cofilin plays an essential role for the rapid turnover of actin filaments by severing and depolymerizing them. The activity of cofilin is repressed by phosphorylation at Ser3 by LIM kinase (LIMK, in which LIM is an acronym of...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Endo, Mitsuharu, Ohashi, Kazumasa, Sasaki, Yukio, Goshima, Yoshio, Niwa, Ryusuke, Uemura, Tadashi, Mizuno, Kensaku
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742113/
https://ncbi.nlm.nih.gov/pubmed/12684437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-07-02527.2003
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