A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia

Cofilin mediates lamellipodium extension and polarized cell migration by stimulating actin filament dynamics at the leading edge of migrating cells. Cofilin is inactivated by phosphorylation at Ser-3 and reactivated by cofilin-phosphatase Slingshot-1L (SSH1L). Little is known of signaling mechanisms...

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Détails bibliographiques
Auteurs principaux: Nagata-Ohashi, Kyoko, Ohta, Yusaku, Goto, Kazumichi, Chiba, Shuhei, Mori, Reiko, Nishita, Michiru, Ohashi, Kazumasa, Kousaka, Kazuyoshi, Iwamatsu, Akihiro, Niwa, Ryusuke, Uemura, Tadashi, Mizuno, Kensaku
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2004
Sujets:
Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172350/
https://ncbi.nlm.nih.gov/pubmed/15159416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200401136
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