A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia

Cofilin mediates lamellipodium extension and polarized cell migration by stimulating actin filament dynamics at the leading edge of migrating cells. Cofilin is inactivated by phosphorylation at Ser-3 and reactivated by cofilin-phosphatase Slingshot-1L (SSH1L). Little is known of signaling mechanisms...

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Detalhes bibliográficos
Main Authors: Nagata-Ohashi, Kyoko, Ohta, Yusaku, Goto, Kazumichi, Chiba, Shuhei, Mori, Reiko, Nishita, Michiru, Ohashi, Kazumasa, Kousaka, Kazuyoshi, Iwamatsu, Akihiro, Niwa, Ryusuke, Uemura, Tadashi, Mizuno, Kensaku
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172350/
https://ncbi.nlm.nih.gov/pubmed/15159416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200401136
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