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The Cofilin Activity Cycle in Lamellipodia and Invadopodia

The actin severing protein cofilin is essential for directed cell migration and chemotaxis, in many cell types and is also important for tumor cell invasion during metastasis. Through its severing activity, cofilin increases the number of free barbed ends to initiate actin polymerization for actin-b...

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Détails bibliographiques
Auteurs principaux: Oser, Matthew, Condeelis, John
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718474/
https://ncbi.nlm.nih.gov/pubmed/19862699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22372
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