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The Cofilin Activity Cycle in Lamellipodia and Invadopodia
The actin severing protein cofilin is essential for directed cell migration and chemotaxis, in many cell types and is also important for tumor cell invasion during metastasis. Through its severing activity, cofilin increases the number of free barbed ends to initiate actin polymerization for actin-b...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718474/ https://ncbi.nlm.nih.gov/pubmed/19862699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22372 |
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