Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells. The mechanisms regulating invadopodium assembly and maturation are not understood. We have dissected the stages of invadopodium assembly and maturation and show that invadopodia use cortactin phosphorylation as a mast...

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Detalhes bibliográficos
Main Authors: Oser, Matthew, Yamaguchi, Hideki, Mader, Christopher C., Bravo-Cordero, J.J., Arias, Marianela, Chen, Xiaoming, DesMarais, Vera, van Rheenen, Jacco, Koleske, Anthony J., Condeelis, John
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733743/
https://ncbi.nlm.nih.gov/pubmed/19704022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200812176
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