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Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation
Invadopodia, actin-based protrusions of invasive carcinoma cells that focally activate extracellular matrix-degrading proteases, are essential for the migration and intravasation of tumor cells during dissemination from the primary tumor. We have previously shown that cortactin phosphorylation at ty...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5099927/ https://ncbi.nlm.nih.gov/pubmed/27824079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36142 |
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