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Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation

Invadopodia, actin-based protrusions of invasive carcinoma cells that focally activate extracellular matrix-degrading proteases, are essential for the migration and intravasation of tumor cells during dissemination from the primary tumor. We have previously shown that cortactin phosphorylation at ty...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Weidmann, Maxwell D., Surve, Chinmay R., Eddy, Robert J., Chen, Xiaoming, Gertler, Frank B., Sharma, Ved P., Condeelis, John S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099927/
https://ncbi.nlm.nih.gov/pubmed/27824079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36142
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