Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells. The mechanisms regulating invadopodium assembly and maturation are not understood. We have dissected the stages of invadopodium assembly and maturation and show that invadopodia use cortactin phosphorylation as a mast...

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Bibliographische Detailangaben
Hauptverfasser: Oser, Matthew, Yamaguchi, Hideki, Mader, Christopher C., Bravo-Cordero, J.J., Arias, Marianela, Chen, Xiaoming, DesMarais, Vera, van Rheenen, Jacco, Koleske, Anthony J., Condeelis, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2009
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733743/
https://ncbi.nlm.nih.gov/pubmed/19704022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200812176
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