Molecular mechanisms of invadopodium formation: the role of the N-WASP–Arp2/3 complex pathway and cofilin

Invadopodia are actin-rich membrane protrusions with a matrix degradation activity formed by invasive cancer cells. We have studied the molecular mechanisms of invadopodium formation in metastatic carcinoma cells. Epidermal growth factor (EGF) receptor kinase inhibitors blocked invadopodium formatio...

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Bibliografiska uppgifter
Huvudupphovsmän: Yamaguchi, Hideki, Lorenz, Mike, Kempiak, Stephan, Sarmiento, Corina, Coniglio, Salvatore, Symons, Marc, Segall, Jeffrey, Eddy, Robert, Miki, Hiroaki, Takenawa, Tadaomi, Condeelis, John
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2005
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171731/
https://ncbi.nlm.nih.gov/pubmed/15684033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200407076
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