Pharmacological Profile of the Selective FAAH Inhibitor KDS‐4103 (URB597)

In the present article, we review the pharmacological properties of KDS‐4103 (URB597), a highly potent and selective inhibitor of the enzyme fatty‐acid amide hydrolase (FAAH), which catalyzes the intracellular hydrolysis of the endocannabinoid anandamide. In vitro, KDS‐4103 inhibits FAAH activity wi...

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Enregistré dans:
Détails bibliographiques
Publié dans:CNS Drug Rev
Auteurs principaux: Piomelli, Daniele, Tarzia, Giorgio, Duranti, Andrea, Tontini, Andrea, Mor, Marco, Compton, Timothy R., Dasse, Olivier, Monaghan, Edward P., Parrott, Jeff A., Putman, David
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Inc 2006
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741741/
https://ncbi.nlm.nih.gov/pubmed/16834756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2006.00021.x
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