The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew)

Considerable evidence implicates the endocannabinoid system as a neuromodulator of nausea and vomiting. The action of anandamide (AEA) can be prolonged by inhibiting its degradation, through the use of URB597 (URB), a Fatty Acid Amide Hydrolase (FAAH) enzyme inhibitor. Here we present evidence that...

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Bibliografiske detaljer
Main Authors:	Parker, LA, Limebeer, CL, Rock, EM, Litt, DL, Kwiatkowska, M., Piomelli, D.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2009
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3781595/ https://ncbi.nlm.nih.gov/pubmed/19239915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2009.02.014
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The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew)

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