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Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models

1. While cannabinoid receptor agonists have analgesic activity in chronic pain states, they produce a spectrum of central CB(1) receptor-mediated motor and psychotropic side effects. The actions of endocannabinoids, such as anandamide are terminated by removal from the extracellular space, then subs...

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Main Authors: Jayamanne, Angelo, Greenwood, Ruth, Mitchell, Vanessa A, Aslan, Sevda, Piomelli, Daniele, Vaughan, Christopher W
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751298/
https://ncbi.nlm.nih.gov/pubmed/16331291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706510
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