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Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine neuropathic pain model

BACKGROUND AND PURPOSE: While cannabinoids have been proposed as a potential treatment for neuropathic pain, they have limitations. Cannabinoid receptor agonists have good efficacy in animal models of neuropathic pain; they have a poor therapeutic window. Conversely, selective fatty acid amide hydro...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Adamson Barnes, Nicholas S., Mitchell, Vanessa A., Kazantzis, Nicholas P., Vaughan, Christopher W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813387/
https://ncbi.nlm.nih.gov/pubmed/26398331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13337
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