Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system

BACKGROUND AND PURPOSE: Elevating levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is a major focus of pain research, purported to be a safer approach devoid of cannabinoid receptor-mediated side effects. Here, we have determined the effects of sustained pharmacologica...

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Autors principals: Okine, Bright N, Norris, Leonie M, Woodhams, Stephen, Burston, James, Patel, Annie, Alexander, Stephen PH, Barrett, David A, Kendall, David A, Bennett, Andrew J, Chapman, Victoria
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449266/
https://ncbi.nlm.nih.gov/pubmed/22595021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02028.x
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