Structural basis for ligand recognition at the human MT(1) melatonin receptor

Melatonin (N-acetyl-5-methoxytryptamine) is a neurohormone that maintains circadian rhythm(1) by synchronization to environmental cues and is involved in diverse physiological processes(2) including blood pressure and core body temperature regulation, oncogenesis, and immune function(3). Formed in t...

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Pubblicato in:Nature
Autori principali: Stauch, Benjamin, Johansson, Linda C., McCorvy, John D., Patel, Nilkanth, Han, Gye Won, Huang, Xi-Ping, Gati, Cornelius, Batyuk, Alexander, Slocum, Samuel T., Ishchenko, Andrii, Brehm, Wolfgang, White, Thomas A., Michaelian, Nairie, Madsen, Caleb, Zhu, Lan, Grant, Thomas D., Grandner, Jessica M., Shiriaeva, Anna, Olsen, Reid H.J., Tribo, Alexandra R., Yous, Saïd, Stevens, Raymond C., Weierstall, Uwe, Katritch, Vsevolod, Roth, Bryan L., Liu, Wei, Cherezov, Vadim
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696938/
https://ncbi.nlm.nih.gov/pubmed/31019306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1141-3
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