Structural basis for ligand recognition at the human MT(1) melatonin receptor

Melatonin (N-acetyl-5-methoxytryptamine) is a neurohormone that maintains circadian rhythm(1) by synchronization to environmental cues and is involved in diverse physiological processes(2) including blood pressure and core body temperature regulation, oncogenesis, and immune function(3). Formed in t...

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Publicado no:Nature
Main Authors: Stauch, Benjamin, Johansson, Linda C., McCorvy, John D., Patel, Nilkanth, Han, Gye Won, Huang, Xi-Ping, Gati, Cornelius, Batyuk, Alexander, Slocum, Samuel T., Ishchenko, Andrii, Brehm, Wolfgang, White, Thomas A., Michaelian, Nairie, Madsen, Caleb, Zhu, Lan, Grant, Thomas D., Grandner, Jessica M., Shiriaeva, Anna, Olsen, Reid H.J., Tribo, Alexandra R., Yous, Saïd, Stevens, Raymond C., Weierstall, Uwe, Katritch, Vsevolod, Roth, Bryan L., Liu, Wei, Cherezov, Vadim
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696938/
https://ncbi.nlm.nih.gov/pubmed/31019306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1141-3
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